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Consolidated BRCA1/2 Variant Interpretation by MH BRCA Correlates with Predicted PARP Inhibitor Efficacy Association by MH Guide
BRCA1/2-Varianten sind prognostische Biomarker für das erbliche Brust- und / oder Eierstockkrebs-Syndrom (HBOC) und prädiktive Biomarker für die PARP-Hemmung.
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Präzisionsonkologie – Die Suche nach Evidenz.
Die molekulare Charakterisierung von Tumoren bei Patienten bietet einen rationalen und vielversprechenden Ansatz, um Onkologen…
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Disease Interception – Onkologie & Genetik: Evidenzbasierte Interception für Prävention und Therapie
Krankheiten erkennen und aufhalten, bevor sie ausbrechen, ist eine faszinierende Vorstellung. Disease Interception hat genau…
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Adverse Event Circumstances and the Case of Drug Interactions.
Adverse events are a common and for the most part unavoidable consequence of therapeutic intervention…
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In Silico Profiling of Clinical Phenotypes for Human Targets Using Adverse Event Data.
We present a novel approach for the molecular transformation and analysis of patient clinical phenotypes…
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Retrospective Side Effect Profiling of the Metastatic Melanoma Combination Therapy Ipilimumab-Nivolumab Using Adverse Event Data.
Recent studies suggest that combining nivolumab with ipilimumab is a more effective treatment for melanoma…
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Bioinformatory-assisted analysis of next-generation sequencing data for precision medicine in pancreatic cancer.
Pancreatic ductal adenocarcinoma (PDAC) is a tumor with an extremely poor prognosis, predominantly as a…