CENTOGENE and Molecular Health Announce an Exclusive Collaboration With the Aim to Transform the Development of Orphan Drugs

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CENTOGENE and Molecular Health Announce an Exclusive Collaboration With the Aim to Transform the Development of Orphan Drugs  

 

  • The combination of real-life data sets in rare diseases with innovative big data/artificial intelligence/novel scientific computational knowledge will transform biomedical research, product development, and therapy.
  • Real-life data and Innovative Bioinformatic Algorithms (RIBA project) will enable the creation of a powerful environment to accelerate, de-risk, and improve the development of new orphan drugs for many diseases and disease areas.
  • RIBA develops and offers data-/computing-driven solutions to guide the highest and most precise innovation for a new way of drug development in a modern biopharmaceutical environment.
  • The collaboration will start with Epilepsy as the first indication

Cambridge, MA, USA & Rostock/Berlin, Germany, and Heidelberg, Germany, July 20, 2020 (GLOBE NEWSWIRE) – Centogene N.V. (Nasdaq: CNTG), a commercial-stage company focused on rare diseases that transforms real-world clinical and genetic data into actionable information for patients, physicians, and pharmaceutical companies, and Molecular Health, a leading company in the field of data and computing science for precision medicine, announced today that they will collaborate exclusively to initiate the Real-life data and Innovative Bioinformatic Algorithms (RIBA) project – starting with Epilepsy as the first indication. RIBA aims to foster a unique novel precision medicine environment to accelerate, de-risk, and improve the development of new orphan drugs based on the combination of large real-life data sets in rare disease with innovative big data, innovative artificial intelligence, as well as computational algorithms and expertise. Both companies are convinced that this strategy of merging real-life data with a global curated biomedical knowledge, as well as applying artificial intelligence and scientific computing will radically change and transform biomedical research, product development, and therapy. Additionally, it will offer data-/computing-driven solutions to guide the highest and most precise innovation for the new way of drug development in a modern biopharmaceutical environment.

 

Prof. Arndt Rolfs, CENTOGENE Chief Executive Officer, stated, “We are excited about this collaboration. Both companies have been analyzing the potential interaction for an extended period of time and are deeply convinced that now is the right time to start an exclusive cooperation focusing on rare genetic diseases. The complementary expertise and knowledge of both companies will allow us to reduce the time to develop a new orphan drug by combining of real-life data and innovative computational biomedical expertise. CentoMD®, one of the world’s largest rare disease data repositories, allows us to take advantage of the high quality of the real-life data from a global cohort of more than 500,000 consented patients. The extraordinary expertise of Molecular Health will not only speed up the identification of new targets in rare disease, but also allow us to de-risk and accelerate the development of new orphan drugs.”

 

“By starting this exciting collaboration between our companies, we are initiating and building a unique novel model of personalized healthcare. The combination of both companies’ data and expertise will ultimately transform modern drug development and therapy. It will allow for the development of better drugs with higher specificity and safety, lower attrition rates in clinical studies, and a faster time to market to help patients with severe diseases worldwide through novel therapies,” said Dr. Friedrich von Bohlen, Molecular Health Chief Executive Officer. “Together with CENTOGENE, Molecular Health´s deep scientific, medical, and computational expertise will lay the fundament for personalized healthcare options in rare diseases to fulfill the promise of precision medicine.”

 

The companies have agreed to start with Epilepsy as the first indication. Financial details were not disclosed.

Leveraging predictive analytics to estimate clinical trial success

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Leveraging predictive analytics to estimate clinical trial success

Estimation of the success likelihood of a clinical trial plays a vital role in determining the time and investment it takes to bring efficacious drug treatment to patients to cure and manage disease. 

 

In an interview with CIO Applications, a Silicon Valley-based tech magazine, Blanca Baez, SVP, Global Head of Pharma & Biotech, and Armin Schneider, SVP of Scientific & Medical Affairs of Molecular Health, share their insights on how the company helps in making unbiased evidence-based clinical development and portfolio  decisions with its technology platform branded MH Predict, by converting clinical and molecular data and medical knowledge into actionable information. Read more at: https://www.molecularhealth.com/wp-content/uploads/2020/05/MH_Predict_Interview_CIO_Applications_6-2020.pdf

 

Important COVID-19 Update from Molecular Health

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Important COVID-19 Update from Molecular Health 

Dear customers and partners,

 

at Molecular Health we share the global concern over the coronavirus pandemic. We want to assure you that we will maintain uninterrupted operation during these challenging times.

 

Our principal investor is Dievini, the investment company of Dietmap Hopp, focusing on innovative biotechnological products and technologies. Also in Dievini’s investment portfolio is the Tübingen-based company CureVac AG, currently in the news as they ramp up their efforts to develop an mRNA-based coronavirus vaccine.

 

Molecular Health’s software identifies the best drugs for individual cancer patients, and our customers – hospitals, laboratories, and patients – depend on us to continue to provide high-quality interpretation of tumours, because, especially now, all patients are entitled to the best healthcare possible.

Our software also enables pharmaceutical companies to improve their research and design more effective clinical trials.

 

In these times of massive transformation, we at Molecular Health have adapted our processes to protect our staff, our partners, and especially those in risk groups:

  • We are keeping our team safe: all our employees are working from home office.
  • We strongly support social distancing: all business meetings with customers and partners are now held virtually. Reach out to your contact person at Molecular Health if you have any questions about an upcoming appointment.
  • We are prepared: if any of our employees should become ill, we will do whatever it takes to remain productive and deliver our services seamlessly.

Thank you for your continued partnership, and please don’t hesitate to contact us if you have any questions or concerns.

 

With kind regards from Heidelberg,

Dr. Friedrich von Bohlen

CEO

Molecular Health starts market entry and product distribution in Eastern Europe

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Molecular Health starts market entry and product distribution in Eastern Europe

As it gains a foothold in European markets, Molecular Health (MH) has started distributing the latest development of its flagship product, Molecular Health Guide (MH Guide), in the Ukraine, Moldova and Romania. This medical application supports oncologists on delivering the right drug to the right patient at the right time – the very essence of personalized medicine.

 

Molecular Health, pioneer in data- and analytics-driven precision medicine, expands its efforts to establish collaborations in Eastern European countries. In cooperation with its partner and distributor, Chisinau-based Oncogene SRL (www.oncogene.eu), Molecular Health starts to bring its technology (Dataome) and products also to hospitals in the Ukraine, Moldova and Romania.

 

First stop of MH’s roadshow was Kyiv. In front of 25 oncologists MH experts and OncoGene delegates presented MH Guide, a treatment decision-support tool which is registered as in-vitro diagnostic medical device (IVD) in Europe and is CE-compliant with European regulations. MH Guide includes all steps of the clinical genomics workflow in oncology, from raw sequencing data to generating an interactive, editable medical report. It is the first product of its kind in Germany to be reimbursed by public health insurances.

 

“Strategic partnerships and collaborations are essential for us to grow, as our regional partners enable us to efficiently bring our products to market,” says Stephan Hettich, Head of Business Development & Sales at Molecular Health, speaking of MH Guide.

 

Next stop was Chisinau, Moldova, before a third opportunity will be taken in March 2020 in Bucharest where MH and Oncogene will exhibit and sponsor the 1st International Congress for Gynecologic Oncology (https://www.icgo2020.eu/).

 

In future, precise and individual approaches in oncological therapy will play an even more important role in diagnosing and treating patients. As tumors become increasingly better genetically characterized and understood, patients very likely will benefit from such highly targeted approaches prior to treatment.

 

 

 

Molecular Health announces collaboration with German private insurer HanseMerkur.

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Molecular Health announces collaboration with German private insurer HanseMerkur: Digitally supported cancer diagnostics improves tumor treatment

 

Hamburg / Heidelberg, October 16, 2019. The widespread disease of cancer has many manifestations and degrees of severity. Promising progress has been made by medicine in recent years with individualized (i.e. genetically adapted to the individual) medicine. Thanks to a cooperation with the Heidelberg-based company Molecular Health, the fully-insured customers of German private insurer HanseMerkur now also benefit from this for certain cancer types.

 

> Continue reading (in German)

 

Die Vereinbarung betrifft Vollversicherte mit der Diagnose einer wiederkehrenden Tumorerkrankung, z. B. einem wiederkehrenden Eierstock-, Eileiter- oder Bauchfellkrebs oder bei einer neuerlichen Tumorerkrankung im Kindes- und Jugendalter.

Die Analyse der Tumor-DNA und ihre anschließende Auswertung ermöglicht es Onkologen, eine optimal auf jeden einzelnen Patienten zugeschnittene Therapie auszuwählen, um die Erfolgsaussichten vor allem bei schweren Krankheitsverläufen zu erhöhen. So können z. B. bei Tumoren, die auf die Standardtherapien nicht ansprechen, oder bei wiederkehrenden Tumoren rasch neue Behandlungsmöglichkeiten erschlossen werden. Ermöglicht wird die erweiterte Diagnostik und Behandlung durch die Software MH Guide, die biologische, molekulare, klinische und pharmakologische Daten in Beziehung setzt – weltweit verfügbares Wissen über Tumorveränderungen und Therapien, auf das die behandelnden Ärzte zugreifen können.

 

Dr. Friedrich von Bohlen, CEO von Molecular Health, erklärt: „Wir freuen uns sehr über den Abschluss der ersten Kooperation mit einer privaten Versicherungsgruppe zu unserem Produkt MH Guide. Die HanseMerkur ist für uns ein idealer Partner, um einer breiten Gruppe an Patienten den Zugang zur onkologischen Präzisionsdiagnostik und
somit den bestmöglichen Therapieoptionen zu eröffnen. Wir sind fest davon überzeugt, dass MH Guide die behandelnden Ärzte gut darin unterstützen wird, informierte, evidenzbasierte und personalisierte Behandlungsentscheidungen für ihre Patienten zu treffen.“

Holger Ehses, Vorstandsmitglied der HanseMerkur Krankenversicherung AG in Hamburg, ergänzt: „Durch den Zugang zu diesem innovativen Instrument der Präzisionsdiagnostik schaffen wir für unsere Versicherten erneut eine verbesserte Versorgung in der Krebsbehandlung. Genetische Analysen spielen in der modernen Krebs-Diagnostik eine zunehmend wichtige Rolle. Durch die Kooperation mit Molecular Health gehen wir einen wichtigen Schritt, unseren umfangreichen Leistungskatalog durch modernste qualitätsgesicherte Angebote zu ergänzen.“

 

Über Molecular Health

Molecular Health ist ein Unternehmen aus dem Bereich der computergestützten Präzisionsmedizin, das mit seinem Fokus auf Data Science und künstlicher Intelligenz die Entscheidungsfindung für Organisationen im Gesundheitssektor verbessert. Die Angebote des Unternehmens basieren auf der Erfassung, Organisation, Integration und Analyse großer Datenmengen aus Biomedizin und Arzneimittelforschung, die mit neuartigen Technologien wie künstlicher Intelligenz und maschinellem Lernen kombiniert werden. Dies erlaubt Ärzten und Patienten eine bessere Diagnose oder Therapieentscheidungen. Weitere Informationen unter www.molecularhealth.com.

 

Über die HanseMerkur

Die HanseMerkur ist mit einem Jahresumsatz von über 2 Mrd. Euro (2018) die einzige selbständige und konzernunabhängige Versicherungsgruppe am Finanzplatz Hamburg. Die Wurzeln des 144 Jahre alten Personenversicherers liegen in der Krankenversicherung, die bis heute die Hauptsparte des Unternehmens ist. Die HanseMerkur ist zudem Spezialist für den privaten Ergänzungsschutz gesetzlich Krankenversicherter und mit rund 1,2 Millionen Zusatzversicherten in diesem Segment einer der größten deutschen Anbieter. In der Privaten Krankenversicherung rangiert sie auf Platz 11 von 41 Anbietern. Darüber hinaus zählt die HanseMerkur zu den größten Unternehmen der touristischen Assekuranz in Deutschland. Weitere Informationen unter www.hansemerkur.de.