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Consolidated BRCA1/2 Variant Interpretation by MH BRCA Correlates with Predicted PARP Inhibitor Efficacy Association by MH Guide
BRCA1/2 variants are prognostic biomarkers for hereditary breast and/or ovarian cancer (HBOC) syndrome and predictive biomarkers for PARP inhibition.
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Radioimmunotherapy in Non-Hodgkin’s Lymphoma: Retrospective Adverse Event Profiling of Zevalin and Bexxar
The power of RWD integration at Molecular Health – insights into the utility and safety of…
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Precision Oncology – The Quest for Evidence.
The molecular characterization of patient tumors provides a rational and highly promising approach for guiding…
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Adverse Event Circumstances and the Case of Drug Interactions.
Adverse Event Circumstances and the Case of Drug Interactions…
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Target-Adverse Event Profiles to Augment Pharmacovigilance: A Pilot Study With Six New Molecular Entities
Peter Schotland, Rebecca Racz, David Jackson, Robert Levin, David G. Strauss and Keith Burkhart…
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In Silico Profiling of Clinical Phenotypes for Human Targets Using Adverse Event Data.
We present a novel approach for the molecular transformation and analysis of patient clinical phenotypes…
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Retrospective Side Effect Profiling of the Metastatic Melanoma Combination Therapy Ipilimumab-Nivolumab Using Adverse Event Data.
Recent studies suggest that combining nivolumab with ipilimumab is a more effective treatment for melanoma…
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Association Between Serotonin Syndrome and Second-Generation Antipsychotics via Pharmacological Target-Adverse Event Analysis
Racz, Soldatos, Jackson, Burkhart. Clin Transl Sci (2018) 00, 1–8; doi:10.1111/cts.12543…
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Bioinformatory-assisted analysis of next-generation sequencing data for precision medicine in pancreatic cancer.
Pancreatic ductal adenocarcinoma (PDAC) is a tumor with an extremely poor prognosis, predominantly as a…
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Comprehensive Benchmarking of SNV Callers for Highly Admixed Tumors
Bohnert, Vivas, Jansen https://doi.org/10.1371/journal.pone.0186175…