Consolidated BRCA1/2 Variant Interpretation by MH BRCA Correlates with Predicted PARP Inhibitor Efficacy Association by MH Guide
BRCA1/2 variants are prognostic biomarkers for hereditary breast and/or ovarian cancer (HBOC) syndrome and predictive biomarkers for PARP inhibition.
Radioimmunotherapy in Non-Hodgkin’s Lymphoma: Retrospective Adverse Event Profiling of Zevalin and Bexxar
The power of RWD integration at Molecular Health – insights into the utility and safety of…
Precision Oncology – The Quest for Evidence.
The molecular characterization of patient tumors provides a rational and highly promising approach for guiding…
Adverse Event Circumstances and the Case of Drug Interactions.
Adverse Event Circumstances and the Case of Drug Interactions…
Target-Adverse Event Profiles to Augment Pharmacovigilance: A Pilot Study With Six New Molecular Entities
Peter Schotland, Rebecca Racz, David Jackson, Robert Levin, David G. Strauss and Keith Burkhart…
In Silico Profiling of Clinical Phenotypes for Human Targets Using Adverse Event Data.
We present a novel approach for the molecular transformation and analysis of patient clinical phenotypes…
Retrospective Side Effect Profiling of the Metastatic Melanoma Combination Therapy Ipilimumab-Nivolumab Using Adverse Event Data.
Recent studies suggest that combining nivolumab with ipilimumab is a more effective treatment for melanoma…
Association Between Serotonin Syndrome and Second-Generation Antipsychotics via Pharmacological Target-Adverse Event Analysis
Racz, Soldatos, Jackson, Burkhart. Clin Transl Sci (2018) 00, 1–8; doi:10.1111/cts.12543…
Bioinformatory-assisted analysis of next-generation sequencing data for precision medicine in pancreatic cancer.
Pancreatic ductal adenocarcinoma (PDAC) is a tumor with an extremely poor prognosis, predominantly as a…
Comprehensive Benchmarking of SNV Callers for Highly Admixed Tumors
Bohnert, Vivas, Jansen https://doi.org/10.1371/journal.pone.0186175…