MH Guide
Translating genomic tumor
profiling into action

MH Guide, a tertiary analysis software, provides molecular pathologists, oncologists, and other healthcare professionals with a reliable tool to interpret NGS or genetic and molecular alteration data. With MH Guide, you can streamline report generation, helping you to manage the current and future demands of precision medicine. You can easily identify the genetic variants relevant for the treatment of your cancer patients and turn that information into actionable clinical knowledge. Take advantage of MH Guide today and experience the benefits of reliable and efficient NGS analysis for precision oncology.

MH Guide, a tertiary analysis software, provides molecular pathologists, oncologists, and other healthcare professionals with a reliable tool to interpret NGS or genetic and molecular alteration data. With MH Guide, you can streamline report generation, helping you to manage the current and future demands of precision medicine. You can easily identify the genetic variants relevant for the treatment of your cancer patients and turn that information into actionable clinical knowledge. Take advantage of MH Guide today and experience the benefits of reliable and efficient NGS analysis for precision oncology.

The link between laboratory results and therapy decisions

MH Guide is designed to streamline communication between treating physicians and diagnosing pathologists. Results from tumor profiling panels are annotated and evaluated in minutes, delivering a structured and clear report for clinical decisions.


IVDR-compliant tertiary analysis

Learn more about important IVDR requirements and how MH Guide can help you comply with them.

Get more information

The value of MH Guide

More than content,
MH Guide is knowledge

With more than 10 years of expertise, we provide valuable insights for your patients and the needs of your institution. Streamline processes, automate workflows, improve accuracy, and make faster, evidence-based decisions. Get the most out of your NGS data with MH Guide.

Service, responsive and dedicated.
MH Guide is for you.

We rely on our customer’s feedback. Thus, offering outstanding service is at our core. We provide expert advice and support for integrating the software into your laboratory to enable accurate, evidence-based reporting for every patient case.

MH Guide builds on quality
without compromise

We provide the highest quality and standards of data privacy and data security. MH Guide is approved as an in-vitro medical device (IVD) in the EU according to the In-Vitro Diagnostics Medical Device Regulation (EU) 2017/746; IVDR. Molecular Health is also CLIA-certified and CAP accredited. MH Guide meets the relevant statutory requirements, including the GDPR in Europe, GenDG in Germany, and the Health Insurance Portability and Accountability Act (HIPAA) in the USA.

MH Guide evolves with you
and with industry practices

MH Guide gives you the insights you need to translate molecular profiles into treatment decisions. Our improved clinical trial matching criteria and algorithm accurately align a patient’s profile with clinical trial eligibility. Our improved case export capability simplifies cohort reporting and analysis. MH Guide brings genomic insights even closer to patients.

Our partner oncologists and pathologists explain MH Guide

Oncologist Prof. Dr. Jalid Sehouli shares how MH Guide supports clinical decisions to offer the best treatment options for cancer patients.

Pathologist Prof. Dr. med. Peter J. Wild and oncologist Prof. Dr. med. Christian Jackisch explain the value of MH Guide in the diagnosis and treatment of cancer.

Stay informed about MH Guide, precision medicine news, and updates on treatment recommendations.

Integrate the right application of MH Guide
into your laboratory routine

For solid and hematological tumors

Discover evidence-based therapy options quickly and accurately with MH Guide for solid and hematologic tumors. Automate the annotation of genetic variants to interpret comprehensive genomic profiling results to provide an overview of clinically-relevant biomarkers and derived therapy options. Streamline your analysis results and benefit from customized reporting for your laboratory needs.

Discover the benefits of automated variant annotation for your clinical routine.

Download our brochure

For hereditary cancers

MH Guide for hereditary cancers is ideal for molecular pathologists, human geneticists, and oncologists looking to quickly, accurately, and efficiently analyze cancer predisposition. Our automated applications support the identification and reporting of clinical-significant germline variants associated with hereditary breast and ovarian cancers (HBOC) and other hereditary cancer predispositions.

The earlier, the better. Turning data into knowledge.

Download our brochure

Frequently asked questions

What is the purpose of MH Guide?

MH Guide is a software as a service product for pathologists, oncologists and other healthcare professionals in cancer diagnosis and molecular diagnostics, treatment, and care. It is designed to help professionals make evidence-based decisions quickly and with greater confidence.

What features does MH Guide offer?

MH Guide is powered by a comprehensive, up-to-date database of clinical evidence and insights, offering patient-specific treatment recommendations and clinical trial matching.

How can MH Guide help pathologists?

MH Guide enables fast, reliable and quality-proven tertiary analysis of NGS data and supports pathologists in streamlining their workflow.

How can MH Guide help oncologists and human geneticists?

MH Guide supports oncologists and human geneticists in making evidence-based treatment decisions based on a patient’s molecular profile.

Which file formats and panels are compatible with MH Guide?

You can use any commercial or proprietary gene panel and have the data analyzed in VCF format with MH Guide. Likewise, whole-exome sequencing (WES) data can be analyzed with MH Guide. The automatically generated reports can be expanded and refined, including results from non-NGS methods (FISH, IHC, (q)PCR). The software generates well-designed, adaptable report templates in PDF and JSON formats.

Is MH Guide secure?

Yes, MH Guide has been designed with privacy and security as a top priority. MH Guide fulfills the highest standards in terms of data privacy and data protection, as well as risk and quality management. Data sovereignty always lies with the user. Confidential patient data is transmitted using advanced encryption standards (SSL/TLS, AES-256).

How frequently is the database updated?

The database is updated on a monthly basis to ensure that healthcare professionals have access to up-to-date information.

How long does it take to learn how to use MH Guide?

Just a few hours. MH Guide is designed to be easy to use and intuitive, reducing the learning curve for healthcare professionals. The Customer Success Team provides the required training, and we are happy to answer any question to get you up and running with the system quickly.

How much does it cost to use MH Guide?

This depends on your requirements. After an initial base fee that includes a case volume, prices are calculated based on the number of analyses and the size of the gene panels to be analyzed. Please contact us for a personalized quote.

How can I try MH Guide?

We offer a free demo of MH Guide to interested healthcare professionals. Simply fill out the form on our website, and a member of our team will be in touch to arrange a time to show you the software.

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