MH Guide - Molecular HealthMolecular Health

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Genome-guided cancer treatment decision support

MH Guide identifies safe and effective therapies for cancer patients by analyzing the cancer’s molecular profile. It matches detected mutations to the world’s knowledge in the field of oncology and helps medical experts to create a patient-specific clinical report.

Finding safe and effective therapies for cancer patients

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MH Guide is a treatment decision support software for oncologists, molecular pathologists, and clinical laboratories. It translates complex genetic data from cancer samples into actionable clinical insights, helping physicians to find targeted therapies, immunotherapies, and clinical trials for their patients, personalized medicine becomes a reality.

Approved for clinical use

Registered as an IVD medical device in the EU, MH Guide is designed for clinical use.

Certified dry-lab

Molecular Health has been CAP- and CLIA-certified since 2016, the first international bioinformatics dry laboratory to achieve this milestone.

Audited quality

Our compliance with rigorous international standards means you can rely on the results with confidence.

Reimbursement contracts

Reimbursement agreements are in place with major payers for pediatric and ovarian cancers, with negotiations in process for other cancer types. 

World-class knowledge database

Medical professionals benefit in their daily practice from actionable clinical insights based on Molecular Health’s proprietary knowledge platform, Dataome. Dataome integrates expert-curated, up-to-date, and medically approved clinico-molecular variant interpretations (CVIs) based on scientific peer-reviewed literature, genome studies, and reference databases.

Independent platform

Molecular Health is an independent provider, and MH Guide is assay-agnostic, capable of analyzing data from a variety of established genetic and molecular tests for cancer.

Streamlined workflow

Focus on the clinically most relevant variants, automatically filtered and matched to CVIs providing personalized, country-specific disease, drug, and clinical trial information for each patient. 

Quick report generation

MH Guide automatically generates individual patient reports that can be refined and signed off by medical experts. Reports use a well-designed, customizable template and can be downloaded in various formats (PDF, json, XML). 


MH Guide’s streamlined workflow allows faster turnover for high throughput of analyses.

Convenient ordering process

Easy to order using MH’s user-friendly ordering application, MH Order portal. 

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Secure data transmission

Sensitive patient data is transmitted and stored using advanced encryption standards (SSL/TLS, AES-256).

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IT infrastructure suits a range of customers, from smaller units to high throughput organizations.

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Flexible input formats

Choose from VCF, FASTQ, BAM.

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Guaranteed patient data security

MH Guide meets the requirements of HIPAA in the US and the GDPR in Europe as well as the GenDG in Germany.

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Suits different use models and budgets

Products available for clinical and research use

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Highly customizable output

Report design, content, and format can be tailored to suit your needs.

Powerful applications for hereditary disease analysis


Molecular Health Guide Mendel (MH Mendel) supports human geneticists to identify clinically significant genetic variants and create a diagnostic report for individual patients. MH Mendel is part of the Molecular Health Guide (MH Guide) solution which is an IVD registered in the EU. 

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Molecular Health Guide BRCA (MH BRCA)
supports medical professionals in identifying and reporting clinically significant germline variants associated with hereditary breast and ovarian cancer (HBOC) syndrome from NGS-based assessment of BRCA1 and BRCA2 and other HBOC related genes. MH BRCA is part of the Molecular Health Guide (MH Guide) solution which is an IVD registered in the EU.

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Dataome - the world’s medical data, cleaned and curated
At the center of action is insight. At the center of insight is Dataome. Built and constructed over a decade, our Dataome technology enables the quality-controlled capture, integration and analysis of clinical and molecular knowledge for millions of patients globally. By connecting real-world patient outcome data to the real-time state of clinical and molecular knowledge, Dataome provides an unparalleled evidence base upon which decision support solutions for the healthcare industry are built.
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Dataome - the world’s medical data, cleaned and curated
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Let’s talk about how our technology can work for you

To find out more, you can call our customer care team or help desk or send us an e-mail. We would be delighted to provide you with more information or answer your questions.

EU: +49 6221 43851-150