CE-in-vitro diagnostic software solutions for your data interpretation
Growing data volumes, constantly increasing biomedical knowledge, more complex analytical procedures, and databases that are insufficiently standardized – these are just some of the challenges that molecular pathology and diagnostic laboratories face. In addition, there is time pressure and increasing demands on data interpretation, for example in molecular tumor boards. Our software solutions help you master these challenges more easily.
Better and faster results
With MH Guide, we have developed in-vitro diagnostic software that allows the analysis of genome variants in comparison with the latest scientific findings – efficiently, precisely, and in line with your requirements. MH Guide helps you interpret data and collaborate directly with clinical colleagues.
Precision oncology demands precision pathology
When suitable for patients, precision medicine is increasingly the first-choice cancer treatment. This places increasing demands on molecular pathology and diagnostic laboratories, since targeted cancer therapies require precision pathology to identify appropriate biomarkers in tumor material or liquid biopsy.
MH Guide enables automated gene variant interpretations from small and large panels for evidence-based results with high quality – even at high testing volumes.
Big data analysis for laboratories – automated variant interpretation via “learning database”
MH Guide, one of the first CE-marked IVD medical devices for molecular diagnostics, compares your NGS test results with relevant biomedical knowledge from current research. To do this, the software draws on one of the world’s largest knowledge bases, Dataome, which continuously processes published biomedical knowledge along with information about drugs and current clinical trials.
MH Guide summarizes the results of this analysis in an informative report, your ideal tool for helping oncologists come to decisions on targeted treatment.
The modules MH Guide/BRCA and MH Guide/Mendel are specifically tailored to the diagnosis of hereditary breast and ovarian cancer syndrome (HBOC) and the needs of human geneticists, respectively.
MH Guide includes a validated process for analyzing NGS data that delivers evidence-based results quickly and comprehensively. This helps your lab increase the quality of result interpretations and simplify report generation – so you are well-equipped to manage all present and future demands that precision medicine entails.
Discover here: the future of automated variant annotation
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How your laboratory benefits
Cloud-based portal
Fast login and quick access to the latest platform version
Rapid results
High-speed clinical annotation and report creation
Simple upload
Easily upload files via encrypted connections
Trusted
Our annotations undergo a rigorous review process
Secure
Data processing in accordance with GDPR, state-of-the-art encryption
Scalable
Review as many variants as you find useful
Platform-independent
Accepts standard file formats from any analysis method
Affordable
Single and volume pricing available
The workflow of MH Guide
How your lab benefits:
- You accurately and comprehensively process large volumes of sequencing data, using our genome analysis pipeline, or process data from your genome analysis pipeline in VCF format.
- You create quality-assured clinical variant annotations faster.
- You benefit from one of the world’s largest databases of biomedical information (Dataome) for variant interpretations according to the latest state of knowledge.
- You benefit from a high degree of customization – define your own filter settings for your reports, filter relevant information for the results report, and maintain your own data and sources. Data sovereignty always remains with you.
- Simple role management allows you to collaborate with oncologists on patient cases – for easier coordination and better preparation of molecular tumor boards.
- We offer comprehensive service and consulting to help you make the most of our applications: Our staff is available to assist you with daily testing as well as research projects as needed, and will work with you to develop customized solutions for your lab.
Efficient, high-quality results
“Increasingly, larger panels are playing a role in molecular testing and variant interpretation. Automated interpretation tools like MH Guide ensure fast and accurate results.”
We have put together a brochure for you to find out more about the benefits and functionality of MH Guide.
PD Dr. med. Christian Meisel
Chief Medical Officer
FAQs
We would be happy to offer you a software demo. Send us your request in writing or call us: +49 6221 43851-150.
MH Guide can process FASTQ and VCF data and offers pathologists highly-automated generation of individual patient reports, each of which can be expanded and refined, including results from non-NGS methods (FISH, IHC, (q)PCR). The software generates well-designed, adaptable report templates in various formats (PDF, JSON, XML).
MH Guide fulfills the highest standards in terms of data privacy and data protection, as well as risk and quality management. Data sovereignty always lies with the user. Confidential patient data is transmitted and stored using advanced encryption standards (SSL/TLS, AES-256).
This depends on your requirements. Prices are calculated based on the number of analyses and the size of the gene panels to be analyzed. We are happy to advise you personally.
MH Guide is the main software application, MH Guide/BRCA and MH Guide/Mendel are special modules. You can find more information here: MH Guide, MH Guide/BRCA, MH Guide/Mendel.
You can use any commercial or proprietary gene panel (small or large) and have the data analyzed in VCF format with MH Guide. Likewise, whole-exome (WES) and whole-genome (WGS) data can be analyzed with MH Guide. Raw data (FASTQ) from gene panels and WES analyses from popular Illumina platforms can be analyzed using MH Guide Premium.
MH Guide allows users to maintain and edit their own annotation data and variant classifications in a personal, secure account area. On request, Molecular Health can assist you in transferring ACMG-compatible variant classifications and descriptions from your own databases to your account.
Yes, you can assign case-related accounts and rights, giving clinical colleagues access to the discussed case.
Our software solutions for the optimal support of laboratory decisions
Dr. Katrin Stecker
Head of Scientific Field Support
“We are working to identify clinically-relevant gene variants as efficiently and reliably as possible. Our goal is to give you the best possible support for your daily analyses and your research projects.”
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© 2020 Molecular Health GmbH
© 2021 Molecular Health GmbH
© 2020 Molecular Health GmbH