MH BRCA | Molecular Health

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Hereditary cancer predisposition analysis of breast and ovarian cancer syndrome (HBOC)

MH BRCA supports medical professionals in identifying and reporting clinically significant germline variants following official genetic guidelines. Create individual patient reports based on NGS data from BRCA1/BRCA2 and other genes associated with hereditary breast and ovarian cancer syndrome.

Knowing the risk for HBOC can mean early detection and prevention

MH BRCA is a diagnostic support software for analysis of HBOC-related genes, in particular BRCA1 and BRCA2, for use by clinical labs, molecular pathologists, and human geneticists. The application analyzes genetic data from a patient’s sample, focusing on germaline variants detected from Molecular Health’s integrated databases and world-standard reference sources and preclassified using ACMG classification criteria. Medical professionals can generate standardized diagnostic reports for individual patients, efficiently and accurately.

Highly-automated report creation

From raw data to a well-designed report in a few clicks

Focus on clinically significant variant

Automatic preclassification using ACMG criteria

Reliability

MH BRCA is subject to a stringent quality process, so you can rely with confidence on the results

World-class knowledge database

MH gathers and structures information from multiple external sources, so users can access regularly updated information on population frequencies, functional impact predictions, variant classifications, and variant-disease correlation.

Convenient ordering process

Benefit from MH’s user-friendly ordering application, MH Order portal, for ordering analyses, uploading NGS data, and tracking orders.


Certified dry-lab

CAP- and CLIA-certified since 2016. MH was the first international bioinformatics dry laboratory to achieve this distinction.

Certified operational quality

MH’s quality management system is ISO 13485-certified.

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SaaS

The application is provided as a Software as a Service (SaaS), so you benefit from standard operating procedures.

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Secure data transmission

Secure transmission of patient data using advanced encryption standards (SSL/TLS, AES-256).

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Scalable

Scalable IT infrastructure to suit a range of labs, from smaller units to high throughput organizations.

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Flexible platform

MH BRCA can process standard sequencing data formats, including VCF and FASTQ. Output formats include PDF, json, or XML.

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Guaranteed patient data security

MH Guide meets the requirements of HIPPA in the US.

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MH Variant detection pipeline

The MH-developed genome analysis pipeline preserves ethnicity-specific variant information using ethnicity-specific reference genomes.

More of our powerful applications for decision support

 

Molecular Health Guide Mendel (MH Mendel) supports human geneticists in diagnosing hereditary diseases and creating diagnostic reports for individual patients. The germline data analysis follows official genetic guidelines and uses ACMG variant classification criteria.


Molecular Health Guide (MH Guide) identifies safe and effective therapies for cancer patients by analyzing the cancer’s molecular profile. It matches detected mutations to the world’s knowledge in the field of oncology and helps medical experts to create a patient-specific clinical report with treatment recommendations.

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Let’s talk about how our technology can work for you

To find out more, you can call our customer service or send us an e-mail. We would be delighted to provide you with more information or answer your questions. 

E-mail: CustomerCareUS@molecularhealth.com