Hereditary disease analysis
MH Mendel supports human geneticists in diagnosing hereditary diseases and creating diagnostic reports for individual patients. The germline data analysis follows official genetic guidelines and uses ACMG variant classification criteria.
Accelerate the assessment of germline variants
MH Mendel is a hereditary disease diagnostic support software for clinical labs, molecular pathologists and molecular geneticists. The application analyzes complex genetic data from a patient’s sample and matches the results to knowledge in Molecular Health’s integrated databases and world-standard reference sources. Variants identified as relevant for a diagnosis are pre- classified so that medical professionals can generate standardized diagnostic reports, efficiently and accurately.
Molecular Health has been CAP- and CLIA-certified since 2016, the first international bioinformatics dry laboratory to achieve this milestone.
Automatic variant classification
Benefit from automated variant pre-classification using standard ACMG terminology to focus on relevant information at a glance.
Unlock knowledge at the genomic level
View genotype-phenotype correlations
Extendable knowledge base
Grow your organization’s knowledge base, as variant classifications are added with every case and immediately available for all colleagues.
Flexible report generation
Generate a diagnostic report using a well-designed standardized template in just a few clicks. If wished, refine the report contents, include additional test results, and type an interpretation. Organizations can customize the layout to suit their needs.
Increase report creation speed
Gene and variant filters can help medical professionals to identify disease-related variants faster.
Easy to integrate
Integrate the analysis smoothly into existing processes: MH Mendel’s flexible interface can analyze a range of standard sequencing data formats.
Consultation with colleagues
Easily share a case with a colleague to get a second opinion.
Convenient ordering process
Benefit from MH’s user-friendly ordering application, MH Order portal, for ordering analyses, uploading NGS data, and tracking orders.
World-class knowledge database
MH gathers and structures information from multiple external sources, so users can access regularly updated information on population frequencies, functional impact predictions, variant classifications, and variant-disease correlation.
The application is provided as a Software as a Service (SaaS), so you benefit from standard operating procedures.
Certified operational quality
MH’s quality management system is ISO 13485-certified and the software design process is IEC 62304 and ISO 14971-certified.
Secure, encrypted storage of patient data with controlled access using user private keys
Secure data transmission
Secure transmission of patient data using advanced encryption standards (SSL/TLS, AES-256)
Scalable IT infrastructure to suit a range of labs, from smaller units to high throughput organizations
Flexible input and output formats
Input formats: choose from VCF, FASTQ, BAM, or XML. Output formats: PDF, json, or XML
Guaranteed patient data security
Meets the requirements of HIPPA in the US, guaranteeing the highest levels of patient data security (HIPPA: Health Insurance Portability and Accountability Act).
Ethnicity-specific variant information
The MH-developed genome analysis pipeline preserves ethnicity-specific variant information using ethnicity-specific reference genomes
Flexible hosting, on local servers, with all client data locally stored
Expand your knowledge base
Import your existing variant classification information and start building a knowledge base for your organization
More of our powerful applications for decision support
Molecular Health Guide (MH Guide) identifies safe and effective therapies for cancer patients by analyzing the cancer’s molecular profile. It matches detected mutations to the world’s knowledge in the field of oncology and helps medical experts to create a patient-specific clinical report with treatment recommendations.
Molecular Health Guide BRCA (MH BRCA) supports medical professionals in identifying and reporting clinically significant germline variants following official genetic guidelines. Create individual patient reports based on NGS data from BRCA1/BRCA2 and other genes associated with hereditary breast and ovarian cancer syndrome.
Let’s talk about how our technology can work for you
To find out more, you can call our customer service or send us an e-mail. We would be delighted to provide you with more information or answer your questions.